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Examples of Upperton's Particle Engineering Capabilities: |
| Product/Process Characteristic | Description |
| Particle Size | Control of particle size is often important. For example both intravenous and pulmonary products have strict size requirements. Reproducibility of the size distribution is also a key factor in a successful product. |
| Particle Wall Thickness | The thickness of the particle wall will have a dramatic effect on powder bulk density and aerodynamic properties, allowing manipulation of powder handling properties. |
| Co-spray Drying | It is possible to spray dry mixtures of compounds. For example a solution containing both a protein and a stabilising sugar can be spray dried to enhance protein stability in the particles. Alternatively a solution of one compound containing a suspension of a second can be spray dried to achieve microencapsulation. |
| Post Spray Drying Modification | Spray dried particles may be chemically modified to change their functional characteristics or surface properties. |