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----- Press Release -----

Upperton Launches Contract Particle Technology Services.

Upperton announces that it is to launch a new contract service, providing a specialised spray drying service to the pharmaceutical industry.

23rd September 2002

Nottingham, UK: Upperton today announced that it is to launch a contract particle technology service to the pharmaceutical industry. This new service is aimed at established pharmaceutical companies that are interested in assessing the use of spray drying at an early stage in the development of their pharmaceutical formulations.

The need for such a service has become apparent in recent years as spray drying becomes an important technology for the pharmaceutical industry. Its suitability for the formulation of a wide range of active ingredients has led to a rapid growth in its use. Such formulation applications include targetting and microencapsulation of both therapeutic and diagnostic agents. The growth in pharmaceutical spray drying is driven by a number of advantages over competing technologies (eg. freeze-drying and micronisation), including lower processing costs, ease of scale-up and particularly speed, with its ability to transform solutions into highly defined particles in seconds.

Upperton is looking to use its considerable experience to assess the suitability of spray drying as a formulation tool at an early stage in product development. This experience will be applied to a customer's product allowing a quick assessment of the ability of spray drying to meet the desired product profile. The spray-dried product will be characterised to agreed specifications and returned along with all manufacturing and analytical data to the customer for evaluation.

Upperton's Founding Director, Dr Richard Johnson, added "This service allows customers to assess the potential of spray drying at a small scale without the need for capital investment. Add to this the experience that Upperton possesses in this field and it is clear that we offer the simplest and most cost effective route to the successful development of spray-dried pharmaceuticals"

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