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----- Press Release -----

Upperton Acquires Extensive Patent Portfolio

Upperton Limited announces the signing of an agreement with Quadrant Healthcare, thereby obtaining an exclusive right to exploit Quadrant's proprietary microparticle technologies in the field of diagnostic imaging.

28th September 2000

Nottingham, UK -- Upperton Limited, an emerging research and development company, has successfully completed the acquisition of a significant intellectual property portfolio from drug delivery company, Quadrant Healthcare.

The agreement between the two companies consists of a combination of patent licences and assignments and gives Upperton an exclusive position to exploit related patents belonging to Quadrant Healthcare in the diagnostic imaging field.

Founding Director, Dr Richard Johnson, was delighted at the successful conclusion of negotiations. The extensive technology portfolio offers a number of exciting opportunities, particularly in the most rapidly growing sectors of MRI and Ultrasound Contrast Imaging. A number of key projects have been identified by Upperton and work in these areas will now proceed rapidly.

Upperton is currently in the process of establishing a number of research programmes at its Nottingham laboratories and is now actively seeking research partners to join in exploiting this exciting technology.

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