+44 (0)115 855 7050 enquiry@upperton.com


26 September 2018 - Upperton Welcomes New Staff

Through extending our capabilities Upperton’s family have grown from three members of  staff four years ago, to twenty-one staff this year. The latest staff updates are:

·         Paul Kelsall, Director of Clinical Trials Manufacturing

Bringing experience in both sterile and non-sterile manufacturing, formulation development and facilities management. Paul formerly worked for Boots, Reckitt Benkiser, Nova Laboratories and Aesica.

·         Sarah Bayliss, Director of Quality & Compliance

Experience of implementing, maintaining and remediating quality management systems. Sarah joins us from Aesica.

·         Thomas Williams, Head of Clinical Manufacturing

Experience in developing and manufacturing investigational medicinal products for Phase I and II clinical trials. Thomas joins us from Quotient Sciences.

·         Rebecca Gray, Senior QC Analyst

Experience in QC testing, early formulation development analysis and analytical method qualification. Rebecca joins us from Quotient Sciences.

·         Klara Fisken, Business Development Associate

Klara joins us from the University of Nottingham, where she has just completed an MSc in Biopharmaceutical Biotechnology and Entrepreneurship.

·         Ella Rose, Junior Project Scientist

Ella joins us from Nottingham Trent University as a year long placement student, where she is currently studying towards a BSc in Chemistry.

19th September 2018 - Extended Pilot Plant Capabilities


Our newly expanded Pilot Plant has enabled us to provide our customers with a seamless transfer of processes from laboratory to clinical trials manufacture. In particular we offer three scales of spray dryer, all of which can also be operated in our GMP plant. Spray dryers in our pilot plant include:

·         ProCepT 4M8-TriX spray dryer

·         Intermediate spray dryer (Upperton design)

·         Niro Mobile Minor

These spray driers can spray dry a range of batch sizes (from 10mg to 3kg), allowing Upperton to conduct feasibility studies at scale to enable rapid transfer and reduce risk on scale up.


30th August 2018 - Successful First Batches from Upperton Clinical Manufacturing Plant


Successful First Batches from Upperton Clinical Manufacturing Plant

Upperton has successfully produced its first batches of product from its clinical manufacturing plant during August.

The inaugural batches were:

·         Spray dried from solutions containing a range of excipients.

·         Spray dried powder was both filled into capsules and tableted.

·         Analytical tests including particle sizing, hardness and dissolution testing were performed.

The Upperton GMP manufacturing team were delighted to successfully complete these initial batches and now look forward to further work for an expanding customer base. To initiate discussions and learn more contact Upperton.



6th July 2018 - Upperton adds Mass Spectroscopy to its analytical capabilities

Upperton adds Mass Spectroscopy to its analytical capabilities

Upperton Pharma Solutions has now completed the installation and commissioning of its Agilent 1100 series LC/MSD (Liquid Chromatography mass selective detector) with ESI (Electrospray ionisation). The new capability will allow Upperton to offer clients molecular mass analysis, useful for assessing purity and detecting API decomposition or modification during formulation processing.

Contact Upperton and discuss how we can use this technique to characterise your API before, during and after formulation and dosage form development

1st June 2018 - 9th International GI-Targeting Seminar

Upperton will be attending the 9th International GI-Targeting Seminar hosted by Evonik in Darmstadt, Germany This 2-days seminar takes place between June 6-7, 2018 and offers attendees hands-on practical sessions in the Evonik laboratories.

21st May 2018 - APS Regulatory Essentials Conference

Upperton Pharma Solutions we will be attending the APS Regulatory Essentials Conference in Loughborough 22nd-23rd May. If you are there, talk to us about your GMP Spray drying requirements

14th March 2018 - Upperton Pharma Solutions to offer cGMP spray drying and clinical trials manufacturing service

Upperton Pharma Solutions is pleased to announce that the company has relocated to larger, self-contained facilities at Highfields Science Park, adjacent to the University of Nottingham. The move to new premises underlines the company’s rapid expansion and will enable it to develop its own cGMP manufacturing capabilities for early phase clinical trials.

The 15,000 square foot facility will house all of the company’s R&D team, as well as its fast-growing Quality Assurance and Manufacturing departments. Within the building is a clean room suite suitable for cGMP manufacture, and a pilot plant for non-GMP intermediate scale manufacturing. Upperton plans to have an MHRA licence for clinical trials manufacturing by Q3 of 2018.

The relocation and expansion will allow the company to offer a full integrated pharmaceutical development service, from early feasibility studies through to cGMP manufacture to support clinical trials. The extended range of capabilities includes:
  • cGMP manufacturing for clinical trials, release testing and QP release
  • Range of additional powder handling and filling capabilities
  • Enhanced dosage form development service
  • Expanded analytical service

In the coming weeks we will be sharing more news about our move and the new services we will be offering our customers.

Upperton R&D Director to speak at Spray Drying Conference on 20th-22nd March 2018

Upperton will be presenting at Spray Drying and Atomisation of Formulations the University of Leeds 20-22nd March 2018 at Faculty of Engineering, Leeds University. The course is the UK’s leading conference dedicated to the science and engineering of spray drying The talk entitled “Spray Drying of Pharmaceuticals” will be given by Dr Andrew Naylor on the 21st March 2018

About Us

With over 20 years of experience we have successfully spray dried, formulated and characterised a vast range of pharmaceutical and biotechnology products for companies across the globe.


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Upperton Pharma Solutions,
Albert Einstein Centre,
Nottingham Science & Technology Park,

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+44 (0)115 855 7050