DRUG PRODUCT DEVELOPMENT & MANUFACTURING

The CDMO for molecules that demand more.

We combine formulation science, analytical expertise and integrated GMP manufacturing to help innovators overcome development challenges and move confidently towards the clinic and beyond.

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ABOUT UPPERTON

One site. One team. Fewer handoffs. Greater Confidence.

Most CDMOs hand your programme on.

Between phases, between teams, between sites – knowledge gets lost, decisions get repeated, and momentum stalls.

Upperton is structured differently.

One site, with senior scientists and leadership who stay close to your molecule from first formulation to final product. R&D, GMP and QC operating without handovers, without gaps, and without the risk that comes from fragmented development.

That’s not how every CDMO works.
It’s how we work.

About Us

Track Record

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Years of drug product development expertise across oral, nasal, pulmonary and parenteral dosage forms.

Routes of delivery

Oral, nasal, pulmonary and injectable drug product development expertise.

GMP MANUFACTURING

Independent GMP manufacturing suites within an integrated 70,000 sq. ft site in Nottingham, UK

EXpertise

experts across R&D, GMP, Analytical and QC on one site

FROM FEASIBILITY TO COMMERCIAL READINESS

Science to Move Your
Molecule Forward.

From formulation development to GMP manufacture, our integrated teams work together to solve technical challenges, reduce programme risk and accelerate progression through development.

01

Formulation Development

Developing solutions for molecules where solubility, stability or delivery challenges limit progress for small molecules and biologics.

02

Analytical Development & Validation

Generating the data, methods and quality controls needed to support confident development decisions.

03

Phase I–II Clinical Supply

Flexible GMP manufacturing and supply solutions supporting first-in-human and early clinical studies.

04

Scale Up for Phase III and Commercial Readiness

Building scalable, manufacturable processes that support successful late phase and commercial preparation.

05

Regulatory and CMC Support

Supporting your development programme with the documentation required for regulatory submissions.

Trusted by innovative drug developers

“Working with Upperton has been exceptional. Their project management approach is marked by outstanding organisation, proactive communication, and a deep commitment to meeting project milestones.”

Independent CMC Consultant, Clinical Stage Biotech

ROUTES OF DELIVERY

Expertise across multiple
Routes of Delivery.

Supporting oral, nasal, pulmonary and injectable drug products through integrated formulation development, analytical testing and GMP manufacturing.

01

Oral

Oral drug product development for tablets, capsules, powders and liquid formulations.

02

Nasal

Supporting local, systemic and nose-to-brain drug delivery through specialist formulation and device expertise.

03

Pulmonary

Dry powder and liquid inhalation drug product development supported by specialist formulation, particle engineering and device expertise.

04

Parenteral

Sterile drug product development, aseptic processing and GMP fill-finish for injectable products.

YOUR STRATEGIC CDMO PARTNER

Built for Small & Mid-size Biotech Companies

We provide fully integrated CDMO services across every stage of the drug product lifecycle.

One Site

Award-winning facility built for scale and continuity providing integrated, end-to-end capabilities delivered under one roof.

One Team

The same team from your early-stage development through to preparation for commercial readiness.

Dosage Form Expertise

Proven track record in solving formulation and delivery challenges across multiple dosage forms.

Executive Leadership on Every Project

Direct access to experienced senior leadership for strategic oversight and decision-making.

Award-winning for our service delivery

Contract Services Award - Upperton Pharma

Quality Assurance Award - Upperton Pharma

Have a molecule that demands more?

Whether you're developing an oral, nasal, pulmonary or sterile drug product, our scientists can help identify the right pathway from development through manufacture.

Speak with an Expert About Us